amid an unsettling report in the present day of tamiflu resistance inside a danish a(h1n1) individual, arrives a review during the new england journal of medicine tracing the swine flu's 90-year evolution.
the present flu strain has genetic roots in an sickness that sickened pigs at a swine present in 1918 in cedar rapids,
office 2010 generator, iowa. a near-century of enhancement given that then might incorporate this flu's accidental resurrection from an extinct strain.
here is what possible went down. simultaneously the 1918 flu pandemic was spreading among people,
office 2010 Professional Plus activation, pigs had been hit which has a comparable respiratory illness. early experiments confirmed the 1918 swine virus along with a human strain emerged about the exact time.
based on the authors from the new paper,
microsoft office 2010 Home And Business 32bit, there was a temporary "extinction" of this strain of virus from humans in 1957. but then it reemerged 20 years later within a small 230-person outbreak in 1976 between soldiers in fort dix,
office 2010 pro plus 32 bit, new jersey. that outbreak did not extend beyond the military base.
however the next 12 months h1n1 reemerged in people within the soviet union, hong kong,
microsoft office 2010 Professional 64bit, and northeastern china. the genetic origin of that 1977 strain turns out not to be the 1976 fort dix strain. instead, it was closely related to a 1950 human strain.
which means that given the genetic similarity of your two strains, reemergence was most likely due to an accidental release during laboratory studies for the 1950 strain that had been preserved as a "freezer" virus.
ouch. hate it when that happens.
the authors hypothesize that concerns about the fort dix outbreak stimulated a flurry of research on h1n1 viruses in 1976, which led to an accidental release and reemergence of your previously extinct virus a year later. the reemerged 1977 h1n1 strain has been circulating in various seasonal influenzas ever since—including today's.
or maybe it wasn't such an accidental a release? conspiracists, restart your engines.
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