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1029919 2010 年 09 月 27 日 09:13 Reading (loading. ..) Comments (0) Category: Science
Berger SI, Ma'ayan A, Iyengar R. Systems pharmacology of arrhythmias. Sci Signal. 2010 Apr 20; 3 (118): ra30.
Abstract | Full Text (PDF) | Full Text (HTML)
Led by biochemist Ravi Iyengar,
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Scientists have identified 13 genes associated with long QT, and the Iyengar team hypothesized that the drugs that cause the arrhythmias act upon the genes' proteins, as well as partnering and neighboring proteins.
To prove this,
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They found that these 1,629 proteins formed their own area, or \,
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Iyengar says these results show that complex diseases can have identifiable boundaries yet may share common molecular features. The overlap, he adds, also indicates that people who have one disease may have the propensity to develop the others.
Hybrid Mode
