The practice of prescribing medication for periods of time or for conditions not FDA-approved is known as off-label use. Although the FDA regulates how a medication can be advertised or promoted by the manufacturer, these regulations do not restrict a doctor's ability to prescribe the medication for different conditions, in different doses
nike high top stilettos , or for different lengths of time.For example the use of more than one weight-loss medication at a time (combined drug treatment) is an example of an off-label use.When it come to losing weight
nike high heel jordans cheap , there are drugs that are recognized to lose a person a lot of weight but there are designed for other conditions. Doctors are known to use such drugs in safe doses for weight loss. Below we look at two such drugs.The first is Buproprion. It is specifically approved as an anti-depressant drug. It is also approved as a smoking cessation drug. It is marketed as Wellbutrin the antidepressant and Zylon the smoking ceasation drug. The drug is associated with clinically significant weight loss of about 5 pounds in 8 weeks. This has prompted it use as an off-label weight loss drug.Bupropion weight loss like other approved weight loss medication like phentermine and sibutramine is also a central nervous system stimulant. It affects neurotransmitters in the brain inhibiting the feeling of hunger. However unlike them, it mainly affects a different set of neurotrnsmitters - dopamine and norepinephrine rather than serotonin. Neurotransmitters are brain chemicals used to send messages with the central nervous system and the brain. They are released by nerve cells and stimulate reception on other cells. Once the message is sent, the neurotransmitters are destroyed or absorbed into the cell that produced them. This is technically referred to as neurotransmitters re-uptake. Bupropion affects dopamine and norepnehrine by inhibiting the re-uptake. Inhibited re-uptake results to the message of the neurotransmitter to be sustained as well as amplified. Dopamine and norepinephrine tend to amplify and sustain the feeling of fullness or satiety. The second major off-label weight loss medication is topiramate which was firstmarketed as Topamax. Topamax in itself is an anti-convulsant developed by Johnson and Johnson for the treatment of seizures disorders; mainly epilepsy. Generic names include Topiramate while brand names include Epitomax. During its clinical trials it was noticed that some participants lost weight without trying. Immediately Johnson and Johnson began trials for Topamax for weight loss. This was in 2002. However the topamax weight loss trials were abandoned after users suffered negative side effects like tingling sensations, fatigue, sleeplessness
jordans women , memory problems etc. Experts were not exactly sure on how topamax effected weight loss. But the people that took the medication described having fewer thoughts about food as well as having a sense of feeling full sooner.
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