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Old 05-26-2011, 08:40 AM   #1
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Old 05-26-2011, 09:40 AM   #2
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1.部位 皮损可发生在全身任何部位,shape up shoes,一般好发于暴露部位、皱褶部位以及易摩擦损伤等部位,也即正常人色素较多的部位。常见于颜面部、颈部、腰 腹部(束腰带)、骶尾部、前臂伸侧与手指背等部位;除皮肤损害外,口唇、阴唇、龟头及包皮内板黏膜也常累及 。白斑多对称分布,也有不少病例损害沿神经节段排列。

2.皮损特点 典型损害处色素完全脱失,呈乳白色,边界清楚,色素脱失的程度也可因人而异。白斑大小、形态不一,数目不定 ,可逐渐增多、扩大,相邻白斑可互相融合而连成不规则的大片,泛发全身,有如地图状。有时白斑中可散在色素 区成岛状,毛发可失去色素以至完全变白,也可正常。在临床上可见因机械性刺激,如腰带对皮肤过紧的压力、摩 擦等促使白斑出现,并称之为同形反应。

3.病情分期 白癜风的病期一般可分为三期,即进行期、静止期和好转期。在进行期时,常见因各种应激状态,如外用药物、机 械刺激、精神创伤、手术等,使正常皮肤出现白斑或使原有白斑扩大、增多,甚至泛发全身;此期易发生同形反应 ,夏季发展快,冬季减慢或停止蔓延。在静止期白斑可停止发展,境界清楚,

白斑边缘色素加深。好转期白斑边缘色素加深并逐渐向白斑中央渗人而使白斑内缩,也有的在白斑中出现毛孔周围 散在岛屿状色素区,白斑的数目也随之逐渐减少。

4.临床分型 临床上按白斑的形态、部位、范围及治疗反应一般分为五型。

局限型:白斑单发或群集于某一部位。

散发型:白斑散在,大小不一,但多对称分布。

泛发型:常由局限型或散发型发展而来,白斑总面积大于体表面积的l/2以上。

肢端型:白斑初发于人体的肢端,如面、手足、指趾等暴露部位。

节段型:自斑按皮节或某一神经分布区分布。

5.诊断与鉴别诊断

本病以乳白色色素脱失为主,无自觉症状,shape up skechers,后天发生。典型白癜风一般诊断不难,但早期脱色不完全、边缘模糊的损害需与以下疾病鉴别,shape ups skechers

贫血痣 是一种先天性减色斑,摩擦局部,skechers women,淡色斑本身不发红,而周围皮肤发红。玻片压诊与周围肤色相同。

无色素痣 沿神经节段单侧分布的花斑状局限性淡色斑。

花斑癣 由糠秕孢子菌所致,圆形、卵圆形淡色斑,skechers shoes

单纯糠疹 圆或椭圆形盖以糠秕状鳞屑的淡色斑。

盘状红斑狼疮 愈后留下脱色斑,有萎缩及毛细血管扩张。

粘膜白斑 白斑多呈网状、条纹状或片状,skechers shape ups,为白色角化性损害,伴瘙痒。
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